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The bactericidal mechanism of nano-silver-graphene oxide com

The bactericidal mechanism of nano-silver-graphene oxide composites has not yet been clearly defined. The researchers believe that the bactericidal properties of composite materials are achieved by the combination of graphene and nano-silver. The process is as follows: First, the composite material is adsorbed on the surface of the bacteria by electrostatic action, and then the nano silver is released, and finally the nano silver particles/ions enter the cells to kill the bacteria.

The bactericidal effect of graphene oxide is reflected in three aspects:
(1) There are a large number of oxygen-containing groups on the graphene oxide sheet, such as hydroxyl groups, carboxyl groups, carbonyl groups, etc. These groups can form hydrogen bonds with sugars or proteins constituting the cell wall, and then graphene oxide encapsulates the cells. Isolate it from the nutrient solution, causing the cells to die without nutrients;

(2) Graphene oxide can be adsorbed on bacterial cells, and its sharp edges can damage the cell membrane, leading to cell damage and death;

(3) Graphene oxide can change the intracellular oxygen partial pressure, causing the intracellular substances to be oxidized and destroy the internal cells. The composition causes cell death.

2.2 Nano silver sterilization mechanism

At present, there are three main mechanisms for the bactericidal action of nano-silver:

(1) Nano-silver is first anchored on the cell wall of bacteria, forming pores with the cell wall, and entering the bacterial cells through these holes, causing leakage of cell components and destruction of cell membranes.

(2) Nano-silver can concentrate the intracellular DNA to a state of tension, and the tight DNA will accumulate in combination with the cytoplasm, causing the loss of cellular material, leading to cell death.

(3) Nano-silver can destroy the interruption of intracellular material transport.